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Kinder chemo

Kinder chemo

作者:湛骁埽  时间:2019-03-07 07:09:00  人气:

CANCER treatments such as radiation or chemotherapy cause unpleasant symptoms because they take their toll on both tumours and healthy tissue. But a novel drug could alleviate these side effects if success in animal trials is matched in people. Andrei Gudkov and his colleagues at the University of Illinois in Chicago suspected that much of the collateral damage is caused by the action of a protein called p53. When they treated mice with pifithrin, which inhibits p53, before exposing them to radiation, the team found that exposures that killed 60 per cent of control mice left the treated animals unharmed (Science, vol 285, p 1733). Since the majority of tumours lack functional p53, the drug should not interfere with most anticancer therapies. “If these drugs work as well in people, we’ll be able to reduce a lot of suffering,